| 產(chǎn)品編號 | BIO0961SM |
| 英文名稱(chēng) | Anti-PD-L1 & VEGF Reference Antibody (Pm8002 Biosimilar) |
| 別 名 | B7-H1 / PD-L1 / CD274 & VEGF; Pm8002 |
| 抗體來(lái)源 | |
| 克隆類(lèi)型 | Monoclonal |
| 交叉反應 | Human |
| 產(chǎn)品應用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 172.48kDa |
| 性 狀 | Lyophilized |
| 亞 型 | IgG-VHH |
| 純化方法 | Protein A |
| 緩 沖 液 | 100 mM Pro-Ac 20mM Arg pH 5.0 |
| 保存條件 | -80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | |
| 產(chǎn)品圖片 |
Pm8002 bound to PD-L1-CHO-K cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ) , and test by flow cytometry. As shown in fig, Pm8002 bound to PD-L1-CHO-K cells, and the EC50 was 3.545 nM.
Pm8002 bound to B7-H1 / PD-L1 / CD274 protein, and then rebounded to secondary antibodies(Anti-Human-κ+λ-HRP) , and read OD450. As shown in fig, Pm8002 bound to in human B7-H1 / PD-L1 / CD274 Protein-His, and the EC50 was 0.02648 nM.
Pm8002 bound to VEGFA protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Pm8002 bound to in human VEGFA Protein-His, and the EC50 was 0.01613 nM.
The purity of Anti-PD-L1 & VEGF Reference Antibody (Pm8002) is 98.79%, determined by SEC-HPLC.
Anti-PD-L1 & VEGF Reference Antibody (Pm8002) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
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