產(chǎn)品編號 | BIO0984SM |
英文名稱(chēng) | Anti-CD3e & Mesothelin & Serum Albumin Reference Antibody (Hpn536 Biosimilar) |
別 名 | CD3e & Mesothelin & Serum Albumin / SA / HSA; Hpn536 |
抗體來(lái)源 | |
克隆類(lèi)型 | Monoclonal |
交叉反應 | Human |
產(chǎn)品應用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 52.92kDa |
性 狀 | Lyophilized |
亞 型 | BiTE |
純化方法 | Protein A |
緩 沖 液 | 100 mM Pro-Ac 20mM Arg pH 5.0 |
保存條件 | -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 | |
產(chǎn)品圖片 |
Co-incubation of Hpn536 with Jurkat cells, then with the addition of CHOK1-MSLN cells for 6 hours. Bright-Lite was used to detect the fluorescent signal. As shown in fig, Hpn536 was able to activate the NF-AT signaling pathway, and the EC50 was 0.033 nM.
Hpn536 bound to MSLN protein, and then rebounded to secondary antibodies(Anti-6*his-HRP ) , and read OD450. As shown in fig, Hpn536 bound to HSA-Fc, and the EC50 was 0.061 nM.
Hpn536 bound to MSLN protein, and then rebounded to secondary antibodies(Anti-human-IgG-Fc-HRP) , and read OD450. As shown in fig, Hpn536 bound to huMSLN-Fc, and the EC50 was 0.374 nM.
The purity of Anti-CD3e & Mesothelin & Serum Albumin Reference Antibody (Hpn536) is 100.00%, determined by SEC-HPLC.
Anti-CD3e & Mesothelin & Serum Albumin Reference Antibody (Hpn536) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
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