| 產(chǎn)品編號 | bs-2946R-Gold |
| 英文名稱(chēng) | Rabbit Anti-HAS1/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標記的透明質(zhì)酸合成酶1抗體 |
| 別 名 | HA synthase 1; HAS; HAS1; HAS 1; HAS-1; HAS1_HUMAN; HuHAS1; Hyaluronan synthase 1; Hyaluronan synthase; HA Synthase: Hyaluronate synthase 1; Hyaluronic acid synthase 1. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 心血管 細胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 信號轉導 干細胞 細胞粘附分子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, ) |
| 產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 65kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Hyaluronan synthase 1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by beta-1,3 and beta-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS1 mRNA shows predominant expression in bone marrow mesenchymal progenitor cells and synovial cells. Function: Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. Similarity: Belongs to the NodC/HAS family. Database links: Entrez Gene: 3036 Human Omim: 601463 Human SwissProt: Q92839 Human Unigene: 57697 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
