| 產(chǎn)品編號 | bs-11433R-Gold |
| 英文名稱(chēng) | Rabbit Anti-DUOXA1/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標記的雙氧化酶成熟因子抗體 |
| 別 名 | DOXA1_HUMAN; Dual oxidase activator 1; Dual oxidase maturation factor 1; duoxa1; NIP; Numb interacting protein; Numb-interacting protein; NUMBIP. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細胞生物 神經(jīng)生物學(xué) 細胞膜蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Pig, Rabbit, ) |
| 產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 38kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DUOXA1 (101-200aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: DUOXA1 is a 343 amino acid multi-pass membrane protein that belongs to the DUOXA family and exists as multiple alternatively spliced isoforms. Expressed almost exclusively in thyroid tissue, but also present in esophageal tissue, DUOXA1 interacts with NUMB and is thought to be essential for the maturation and transport of functional DUOX1 from the endoplasmic reticulum to the plasma membrane. The gene encoding DUOXA1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. Subunit: May interact with NUMB. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Specifically expressed in thyroid gland. Also detected in esophagus. Similarity: Belongs to the DUOXA family. Database links: UniProtKB/Swiss-Prot: Q1HG43.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
