| 產(chǎn)品編號 | bs-13347R-BF488 |
| 英文名稱(chēng) | Rabbit Anti-GGN/BF488 Conjugated antibody |
| 中文名稱(chēng) | BF488標記的配子生成素抗體 |
| 別 名 | FLJ35713; Gametogenetin; MGC33369; GGN_HUMAN. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細胞生物 發(fā)育生物學(xué) 干細胞 細胞凋亡 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Sheep, ) |
| 產(chǎn)品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 67kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GGN/Gametogenetin |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Gametogenetin is a 652 amino acid protein that is primarily expressed in testis and ovary. Interacting with POG (proliferation of germ cells), GGNBP1 and LCRG1, gametogenetin is likely involved in spermatogenesis. Gametogenetin exists as three alternatively spliced isoforms commonly known as gametogenetin protein 1 (GGN1), gametogenetin protein 2 (GGN2) and gametogenetin protein 3 (GGN3), which localize to nuclear membrane, cytoplasm and nucleus/nucleoli, respectively. GGN1 contains two transmembrane domains in its N-terminal half and 2 C-terminal arginine- and lysine-rich nucleolar targeting sequences. GGN1 and GGN3 are likely linked to germ cell development and both GGN1 and GGN2 may be involved in cell trafficking. Function: Gametogenetin gene is a germ cell specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. Subunit: Interacts with FANCL, GGNBP1 and ZNF403/GGNBP2. Database links: Entrez Gene: 199720 Human Entrez Gene: 243897 Mouse Omim: 609966 Human SwissProt: Q86UU5 Human SwissProt: Q80WJ1 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
