| 產(chǎn)品編號 | bs-41361R |
| 英文名稱(chēng) | TMPRSS2 Rabbit pAb |
| 中文名稱(chēng) | 絲氨酸蛋白酶10抗體 |
| 別 名 | Epitheliasin; PRSS10; Serine protease 10; TMPRSS2; TMPRSS2 ERG FUSION GENE, INCLUDED; TMPRSS2 ETV1 FUSION GENE, INCLUDED; TMPS2_HUMAN; Transmembrane protease serine 2 catalytic chain; Transmembrane protease, serine 2; Transmembrane protease, serine 2, EC 3.4.219; Transmembrane protease, serine 2, EC 3.4.219; D16Ertd61e. |
| 研究領(lǐng)域 | 腫瘤 細胞生物 神經(jīng)生物學(xué) 激酶和磷酸酶 腫瘤細胞生物標志物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Human (predicted: Mouse,Rat) |
| 產(chǎn)品應用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant human TMPRSS2 protein: 108-492/492 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Variants
ProteinsPrimary AntibodiesELISAsAntibody ArraysActivity Assays
ProteinsAntibodiesAssaysGenesshRNAPrimersCRISPRLentiviral Particles
CRISPR Knockout KitsgRNAKO PoolsiPSC SNV CloneFree Bioinformatics Tools
C. elegans TransgenicsZebrafish Genome EditingHumanized animal models
Aliases for TMPRSS2 Gene
Aliases for TMPRSS2 Gene
GeneCards Symbol: TMPRSS2 2
Transmembrane Serine Protease 2 2 3 5
PRSS10 2 3 4 5
Transmembrane Protease, Serine 2 2 3
Transmembrane Protease Serine 2 3 4
Serine Protease 10 3 4
EC 3.4.21.109 48
Epitheliasin 3
EC 3.4.21.- 4
EC 3.4.21 48
External Ids for TMPRSS2 Gene
HGNC: 11876 NCBI Entrez Gene: 7113 Ensembl: ENSG00000184012 OMIM®: 602060 UniProtKB/Swiss-Prot: O15393
Previous GeneCards Identifiers for TMPRSS2 Gene
GC21M039410 GC21M041757 GC21M041756 GC21M041750 GC21M042836 GC21M028305
Summaries for TMPRSS2 Gene
Entrez Gene Summary for TMPRSS2 Gene
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020] SWISS: O15393 Gene ID: 7113 Database links: Entrez Gene: 7113 Human Entrez Gene: 50528 Mouse Omim: 602060 Human SwissProt: O15393 Human SwissProt: Q9JIQ8 Mouse Unigene: 439309 Human Unigene: 276145 Mouse Unigene: 81082 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human HeLa cell lysates
Primary: Anti-TMPRSS2 (bs-41361R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 58 kDa
Measured by its binding ability in a indirect ELISA. Immobilized Human TMPRSS2 protein, His Tag (Cat. bs-41361P) at 2 μg/mL (100 μL/well) can bind ?Rabbit Anti-Human TMPRSS2 Antibody, the EC50 is 118.5 ng/mL.
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