| 產(chǎn)品編號 | bs-4649R-Gold |
| 英文名稱(chēng) | Rabbit Anti-Parvovirus Capsid protein VP1/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標記的大鼠細小病毒H-1株(H-1)抗體 |
| 別 名 | Parvovirus h-1 coat; CAPSD_PAVHH; Capsid protein VP1; Coat protein VP1; H-1 Parvovirus Capsid protein VP1. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 細菌及病毒 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | |
| 產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 81kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from H-1 parvovirus Capsid protein VP1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
Function: Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus. Subcellular Location: Virion. Host nucleus. Similarity: Belongs to the parvoviridae capsid protein family. Database links: UniProtKB/Swiss-Prot: P03136
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 大鼠H-1病毒株是由Toolan(1960)從經(jīng)大鼠傳代的人腫瘤細胞系(HEP-1)分離到得第2株大鼠細小病毒(RPV),通常稱(chēng)為H-1病毒,又稱(chēng)Toolan病毒。 |
