| 產(chǎn)品編號 | bs-0065R-BF350 |
| 英文名稱(chēng) | Rabbit Anti-Substance P/BF350 Conjugated antibody |
| 中文名稱(chēng) | BF350標記的P物質(zhì)抗體 |
| 別 名 | Hs.2563; Neurokinin 1; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide gamma; NKA; NKNA; PPT; Protachykinin 1 precursor; Substance K; Substance P; TAC1; TAC2; Tachykinin 1; Tachykinin 2; Tachykinin precursor 1; Tachykinin1; TACI; TKN1_HUMAN. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | Mouse, Rat, (predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, G) |
| 產(chǎn)品應用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 1.4/13kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Substance P |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Subcellular Location: Secreted. Similarity: Belongs to the tachykinin family. Database links: Entrez Gene: 6863 Human Entrez Gene: 21333 Mouse Omim: 162320 Human SwissProt: P20366 Human SwissProt: P41539 Mouse Unigene: 2563 Human UniProtKB/Swiss-Prot: P20366.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. P物質(zhì)（Substance P）是腦組織及消化道中發(fā)現的一種神經(jīng)遞質(zhì)肽。由130個(gè)氨基酸殘基組成，胃腸道中肌肉收縮的有力促進(jìn)劑，亦為強血管擴張劑。 SP是一種腦腸肽，亦是最早發(fā)現的一種神經(jīng)肽，屬于速激肽家族成員，它廣泛分布于中樞及外周神經(jīng)系統，作為一種神經(jīng)遞質(zhì)或調質(zhì)參與疼痛、免疫、心血管等多種生理功能的調節。SP與其它的遞質(zhì)或調質(zhì)類(lèi)似，能作用于多種類(lèi)型的受體，速激肽家族有NK1、NK2、NK3三種受體，都能與SP結合，其中NK1與SP的結合能力最強而被稱(chēng)為SP受體。 |
