| 產(chǎn)品編號 | bs-15584R-RBITC |
| 英文名稱(chēng) | Rabbit Anti-PLAC8 /RBITC Conjugated antibody |
| 中文名稱(chēng) | 羅丹明（RBITC）標記的胎盤(pán)特異基因8蛋白抗體 |
| 別 名 | C15; Onzin; PLAC8; PLAC8_HUMAN; Placenta specific 8; Placenta-specific gene 8 protein; Protein C15. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PLAC8 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: PLAC8 is a 115 amino acid protein belonging to the cornifelin family that is expressed at high levels in plasmacytoid dendritic cells and other organs of the immune system including lymph nodes, spleen, bone marrow and peripheral blood leukocytes, with lower expression in appendix, thymus and fetal liver. Human PLAC8 shares 83% homology with murine PLAC8, where it has been identified in placenta from 9.5-18.5 days postcoitum. The gene encoding PLAC8 maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease Function: Subunit: Tissue Specificity: Expressed at high levels in plasmacytoid dendritic cells. High expression in spleen, lymph nodes, peripheral blood leukocytes, and bone marrow, with lower expression in thymus, appendix, and fetal liver. Post-translational modifications: DISEASE: Similarity: Database links: Entrez Gene: 51316 Human Omim: 607515 Human SwissProt: Q9NZF1 Human Unigene: 546392 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
