| 產(chǎn)品編號 | bs-17306R-BF488 |
| 英文名稱(chēng) | Rabbit Anti-SFXN1/BF488 Conjugated antibody |
| 中文名稱(chēng) | BF488標記的三羧酸載體蛋白SFXN1抗體 |
| 別 名 | FLJ12876; SFXN1; SFXN1_HUMAN; Sideroflexin 1; Sideroflexin-1; TCC; Tricarboxylate carrier protein. |
| 規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 細胞生物 神經(jīng)生物學(xué) 信號轉導 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, ) |
| 產(chǎn)品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SFXN1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The sideroflexin (SFXN) family is comprised of SFXN1, SFXN2, SFXN3, SFXN4 and SFXN5. SFXN1, also designated tricarboxylate carrier protein TCC, is the most highly characterized family member. The ubiquitously expressed SFXN1 protein resides as an integral protein of the mitochondrial inner membrane. It functions as an essential component of the shuttle system that transports mitochondrial acetyl-CoA into the cytosol, where lipogenesis occurs. The SFXN1 gene is mutated in flexed-tail (f/f) mice, which display axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondiral iron deposits in erythrocytes. Therefore, SFXN1 is also thought to facilitate the transport of a component required for iron utilization into mitochondria. All SFXN family members show expression in pancreatic islet cells. SFXN5 displays a citrate transport activity and is primarily expressed in brain. Function: Might be involved in the transport of a component required for iron utilization into or out of the mitochondria. Subcellular Location: Mitochondrion membrane. Similarity: Belongs to the sideroflexin family. Database links: Entrez Gene: 94081 Human Entrez Gene: 14057 Mouse GenBank: NM_022754 Human SwissProt: Q9H9B4 Human SwissProt: Q99JR1 Mouse Unigene: 369440 Human Unigene: 134191 Mouse Unigene: 115752 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
